Chemo-Scale

Blood-based chemosensitivity testing

About

About chemo-scale

Cancer is an extremely heterogenous disease. It progresses differently in each patient and should therefore be treated individually. Many standard therapies only take certain characteristics of the tumour into account, or fail to do so at all. If the therapy fails, recurrence occurs, which is usually more aggressive. It is important that the characteristics of the tumour are studied comprehensively before deciding the treatment plan in order to tailor the therapy to the individual patient and their disease.

Datar Cancer Genetics has proven the clinical relevance of chemo-scale with trials comprising more than 5.000 patients.

chemo-scale is an analysis of tumour cells to provide drug efficacy and
resistance guidance for chemotherapy

With chemo-scale analysis, we minimise the risks of therapy failure for the patient – saving money,
reducing ‘trial and error’ and most importantly, intensifying the attack on the patient’s cancer, not the patient. In addition, the patient benefits from treatments that are not only more effective, but also have fewer side effects.

• chemo-scale directly tests the effect of chemotherapy / anti-cancer drugs on the patient’s tumour cells. It helps to customise the treatment plan to sensitivity and resistance patterns of tumour cells.
• With this information, the physician and the patient can choose the most effective chemotherapy from the available options.
• chemo-scale is perfomed on circulating tumour associated cells (C-TACs) isolated from peripheral blood. A control analysis is included.
• Analysing the chemosensitivity pattern of C-TACs and tumour tissue derived cells of the same patient, we observed a concordance of 93.7%.

chemo-scale is particularly recommended for cancer patients …………………………………………………………………..

… who are newly diagnosed with a solid tumour such as stomach, pancreas, breast etc.

… where cancer has relapsed

KKK?

Kohandatud diagnoosimise lahendused, mis viivad tõhusate raviplaanideni. Oleme eesliinil vähidiagnostika teadusuuringutes.

• The key difference between other tests and chemo-scale is that Datar Cancer Genetics
uses a different approach through which more relevant cells can be identified in the early
phase of the disease in short-term culture, enabling a more precise recommendation (see
publications).
• While cytotoxic chemotherapy is a common therapy option in most solid tumours,
conventional molecular tests mainly provide information on targeted therapy drugs.
• chemo-scale evaluates the actual response of cancer cells to cytotoxic chemotherapeutic
agents.
• chemo-scale is clinically validated on more than 5.000 patients.

chemo-scale is a powerful analysis performed on live tumour cells. It reveals which
drugs will kill the cancer of an individual patient more effectively.

Not all drugs work the same on all patients. Some drugs may not prove
benefical for the patient and waste valuable time and resources at a critical
point in treatment. With chemo-scale there is a way to know how
effective the chemotherapy will be, before starting the treatment.
In clinical trails, comparing the efficacy of chemoresistency profile
with the radiological response focusing on disease progression,
we found a concordance of 87% (combining all tumour
stages).

Täpne ja põhjalik analüüsidelement

Exacta uuringud pakuvad süvitsi minevat teavet kasvaja omadustest. Meie analüüsid aitavad mõista kasvaja bioloogiat tervikuna.

Isikupärastatud ravistrateegiad

Kombineerime unikaalseid biomarkereid, et genereerida raviplaane, mis arvestavad iga patsiendi individuaalsete vajadustega. Teeme koostööd arstidega, et saavutada parimad tulemused.

Raamistiku avardamine

Exacta laiendab diagnostilisi võimalusi haruldaste ja agressiivsete kasvajate korral, pakkudes kvaliteetseid lahendusi ka keeruliste juhtumite jaoks.

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